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Safety

Tirzepatide

Adverse-event report summary for Tirzepatide, drawn from the FDA Adverse Event Reporting System (FAERS).

Total reports
2,641
Reports flagged serious
1,463

“Serious” is FAERS’s own report-level flag (e.g. death, hospitalization, or another outcome the reporter marked as serious) and does not indicate a verified or compound-caused outcome.

Most frequently reported reactions

  1. Product Tampering408 reports
  2. Nausea327 reports
  3. Vomiting279 reports
  4. Diarrhoea231 reports
  5. Fatigue132 reports
  6. Constipation130 reports
  7. Off Label Use120 reports
  8. Drug Interaction104 reports
  9. Headache90 reports
  10. Drug Ineffective88 reports
  11. Abdominal Pain85 reports
  12. Incorrect Dose Administered84 reports
  13. Dizziness83 reports
  14. Abdominal Pain Upper77 reports
  15. Weight Decreased77 reports

Counts reflect the most-reported reaction terms (MedDRA preferred terms) associated with reports naming this compound. A single report can list multiple reactions, so reaction counts need not sum to the total number of reports.